Christian McCaffrey injures knee, will not return vs. Bills

Photo by Stacy Revere/Getty Images

49ers running back Christan McCaffrey appeared to come up limp and had to slide down without contact in the second quarter against the Bills. We’ll update the injury information as it comes in

9:50 p.m. update: The 49ers announced McCaffrey won’t return during the game due to the knee injury.

9:05 p.m. update: The 49ers have announced McCaffrey is questionable to return due to a knee injury.

9:02 p.m. update: McCaffrey walked back to the locker room with the 49ers trainer. He was able to walk without assistance, but his status is uncertain.

Christian McCaffrey is headed to the #49ers locker room

(@jenniferleechan.bsky.social) 2024-12-02T02:01:37.810Z

The San Francisco 49ers have received some kind of scare in the second quarter against the Buffalo Bills. Running back Christian McCaffrey took a pitch and quickly slid down to the field for a five yard loss. He quickly hobbled off the field after the play. On the replay, he was quickly gimpy as he caught the pitch and started running.

yikes — Christian McCaffrey pic.twitter.com/RiwvgHWpjU

— ᑭᖇO ᖴOOTᗷᗩᒪᒪ ᒍOᑌᖇᑎᗩᒪ (@NFL_Journal) December 2, 2024

McCaffrey left the game with 53 rushing yards and 14 receiving yards. He has gone into the injury tent. More to come.

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